Kyle Loh, PhD

2011 Hertz Fellow
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Kyle Loh is an Assistant Professor of Developmental Biology (Stem Cell) at Stanford University.

Kyle’s laboratory at the Stanford Institute for Stem Cell Biology & Regenerative Medicine and the Department of Developmental Biology is focused on generating human tissue progenitors from embryonic stem cells and exploring their use in regenerative medicine (https://loh.stanford.edu/). To this end, they have delineated a comprehensive roadmap that describes how embryonic stem cells can develop into a spectrum of over twenty different human cell types. This roadmap enabled generation of rather uniform populations of human liver progenitors, bone progenitors and heart progenitors from embryonic stem cells, each of which could generate their respective tissue upon injection into respective mouse models. This platform to produce these engraftable human tissue progenitors provides fundamental building blocks for regenerative medicine and provides an ideal venue to understand human developmental biology. In particular, Kyle is interested in questions regarding cellular signaling, developmental competence and tissue organization.

Kyle received his B.A. from Rutgers University, interned with Bing Lim at the Genome Institute of Singapore, and received his Ph.D. from Stanford University (working with Irving Weissman) as a fellow of the Hertz Foundation, the National Science Foundation and the Davidson Institute of Talent Development. He then continued research as the Siebel Investigator at the Stanford Institute for Stem Cell Biology & Regenerative Medicine, and later, as an Assistant Professor of Developmental Biology and The Anthony DiGenova Endowed Faculty Scholar. Kyle is a Packard Fellow, Pew Scholar, Human Frontier Science Program Young Investigator and Baxter Foundation Faculty Scholar, and his research has been recognized by the NIH Director’s Early Independence Award, Forbes 30 Under 30, Harold Weintraub Graduate Award, Hertz Foundation Thesis Prize and the A*STAR Investigatorship.

Graduate Studies

Stanford University
Biology
A Developmental Roadmap for the Diversification of Human Tissue fates from Pluripotent Cells

Undergraduate Studies

Rutgers University

Awards

2017, Director’s Early Independence Award, National Institutes of Health
2018, Forbes “30 Under 30: Science”, Forbes
2018, Hertz Thesis Prize, Fannie & John Hertz Foundation
2018, Baxter Foundation Faculty Scholar
2019, Packard Fellow, David & Lucile Packard Foundation
2019, Pew Biomedical Scholar
2019, Human Frontier Science Program Young Investigator

Related News

Apr 10, 2019
Now an assistant professor at Stanford, Kyle Loh aims to artificially generate human tissues from embryonic stem cells for patients in need.
Mar 26, 2019
We asked some of our current fellows to share their thoughts on topics ranging from their hopes for science and the world to the visionaries they most admire.
Nov 13, 2018
Forbes’ 2019 “30 Under 30” list includes three Hertz Fellows leading the way in healthcare innovation: Megan Blewett, Kyle Loh and Cameron Myhrvold.
Mar 22, 2018
Loh's dissertation provides a roadmap for developing stem cells into pure cultures of human tissue.
Oct 27, 2017
Hertz Foundation Fellows Recognized with 2017 NIH Director’s New Innovator Award, Transformative Research Award and Early Independence Award; Hertz Fellow Edward Boyden is the Most Honored Investigator with Five Awards Since 2007
Aug 1, 2016
Imagine if instead of waiting for months or even years on an organ donor list for a new kidney or heart, scientists were able to grow one for you, on-demand, in a petri dish.